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Modes of testosterone replacement therapy application include
bioidentical testosterone cream or gel, testosterone injections,
testosterone lozenges, testosterone pellets and patches.
Exploring the contraindications and side effects of testosterone
replacement therapy and bioidentical hormones for men.
Bioidentical testosterone cream or gel - testosterone replacement therapy TRT
In the majority of situations, transdermal bioidentical testosterone cream or bioidentical testosterone gel is the best form of natural testosterone replacement therapy. Bioidentical testosterone cream applied to the skin is well tolerated and easily absorbed. This type of testosterone does not affect the liver, and usually requires application only once per day. Most doctors who specialize in bioidentical hormones prefer this mode of natural testosterone replacement therapy.
Bioidentical testosterone lozenges - testosterone replacement therapy TRT
Bioidentical testosterone in a form of sublingual lozenges is also well absorbed, does not affect the liver, but has a very short half-life and therefore requires frequent doses taken several times per day. For this reason, not too many bioidentical hormones doctors use this method of testosterone replacement therapy.
Testosterone injections - testosterone replacement therapy TRT
Testosterone can be replaced by intramuscular injections of testosterone esters (cypionate or enanthate). Intramuscular testosterone injections have unfortunately erratic effects and they do not provide a steady level of testosterone. Therefore, testosterone injections are not always the preferred choice of testosterone replacement therapy by the majority of hormone doctors.
Natural transdermal testosterone patches -
Testosterone replacement therapy TRT
Natural transdermal testosterone patches are commercially available; however they have limited value because their dose is very small, they frequently cause skin irritation and are expensive. Doctors specializing in bioidentical hormones avoid this technique of natural testosterone replacement therapy for men.
Bioidentical testosterone pellets - testosterone replacement therapy TRT
Bioidentical testosterone pellets implanted subcutaneously can be useful in less compliant patients because they require fewer applications. However, bioidentical testosterone pellets necessitate a minor surgical procedure in order to insert the pellet under the skin and there is no possibility of adapting the dose of bioidentical testosterone if needed. A number of doctors specializing in bioidentical hormones for men utilize bioidentical testosterone pellets.
Natural testosterone oral tablets - testosterone replacement therapy TRT
Oral bioidentical testosterone in a form of tablets or capsules is not recommended due to its negative effects on the health of the liver. Oral testosterone tablets cause toxicity to the liver and disrupt normal liver function. Consequently, bioidentical hormones doctors do not use this type of testosterone replacement therapy.
Enhancing natural testosterone replacement therapy TRT
Bioidentical testosterone replacement therapy can be augmented by a good diet, maintaining proper weight, managing stress levels, avoiding drugs, excess alcohol and caffeine. Marihuana decreases all sex hormones including testosterone. Pesticides have very negative effects on testosterone and sperm production. Beta-blockers and cholesterol lowering drugs negatively affect normal testosterone levels in men. Foods rich in fiber cause a significant loss of testosterone and other hormones in stool and decrease the available levels of testosterone. Avoiding these items will serve to enhance the body’s ability to produce natural testosterone and will boost the effectiveness of natural bioidentical testosterone replacement therapy.
Side effects of testosterone replacement therapy
Natural bioidentical testosterone replacement therapy does not have the same side effects and risks as synthetic androgens (synthetic testosterone replacement therapy). Bioidentical testosterone replaced in physiological doses has very few known side effects.
Contraindications of bioidentical testosterone replacement therapy
The contraindications to bioidentical testosterone replacement therapy in men are prostate cancer and breast cancer (breast cancer is a condition that is rare in men). Patients who have active prostate cancer are advised not to use testosterone replacement therapy as this can increase the growth of cancerous cells in the prostate gland.
Other hormonal systems that influence testosterone replacement therapy:
Thyroid hormones - testosterone replacement therapy
Thyroid hormones increase natural testosterone activity. Bioidentical testosterone replacement therapy will increase thyroid hormone production. Patients with a thyroid hormone dysfunction in the form of hypothyroidism or hyperthyroidism, should have their thyroid hormone levels assessed by an experienced doctor who specializes in bioidentical hormones.
Adrenal hormones - testosterone replacement therapy
The hormones DHEA and cortisol are secreted by the adrenal cortex. Natural testosterone replacement therapy will increase DHEA activity while decreasing cortisol activity. DHEA therapy can aggravate a cortisol deficiency. Emotional stress resulting in increased cortisol output by the adrenal glands will counteract the effects of bioidentical testosterone replacement therapy and this will require an increased dose of testosterone. Doctors specializing in bioidentical hormones advise men who are on natural testosterone replacement therapy to implement stress reduction methods. Reducing stress levels will render natural testosterone replacement therapy more effective. An optimal way to support the adrenal glands is through the use of natural adrenal support supplements.